KHDC1 anticorps (AA 30-80)

N° du produit ABIN5690030

Cet anticorps anti-KHDC1 Polyclonal Lapin (ABIN5690030) détecte spécifiquement KHDC1 dans ELISA, WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KHDC1 anticorps (AA 30-80) (ABIN5690030)

Antigène: KHDC1 (KH Homology Domain Containing 1 (KHDC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDC1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KHDC1 anticorps

Épitope: AA 30-80

Specificité: KHDC1 antibody is human, mouse and rat reactive. At least three isoforms of KHDC1 are known to exist, this antibody will only detect the longest isoform.

Purification: KHDC1 Antibody is affinity chromatography purified via peptide column.

Immunogène: KHDC1 antibody was raised against a 15 amino acid peptide near the amino terminus of human KHDC1.

The immunogen is located within amino acids 30 - 80 of KHDC1.

Isotype: IgG

Information d'application

Indications d'application: KHDC1 antibody can be used for detection of KHDC1 by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KHDC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: KHDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KHDC1

Antigène: KHDC1 (KH Homology Domain Containing 1 (KHDC1))

Autre désignation: KHDC1

Sujet: KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).

Poids moléculaire: Predicted: 18 kDa

Observed: 26 kDa

ID gène: 80759

NCBI Accession: NP_085045

UniProt: Q4VXA5