KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.
Purification
KIRREL3 antibody is affinity chromatography purified via peptide column.
Immunogène
KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.
The immunogen is located within amino acids 20 - 70 of KIRREL3.
KIRREL3
Reactivité: Souris
FACS, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
Alexa Fluor 350
Indications d'application
KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
KIRREL3 antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
KIRREL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
anticorps KIRRE, anticorps MRD4, anticorps NEPH2, anticorps PRO4502, anticorps 1500010O20Rik, anticorps 2900036G11Rik, anticorps SST4, anticorps mKIAA1867, anticorps kirre like nephrin family adhesion molecule 3, anticorps kin of IRRE like 3 (Drosophila), anticorps KIRREL3, anticorps Kirrel3
Sujet
KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).