NOSTRIN anticorps (AA 430-480)

N° du produit ABIN5690080

L’anticorps anti-NOSTRIN Polyclonal Lapin est utilisé pour la détection de NOSTRIN dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour NOSTRIN anticorps (AA 430-480) (ABIN5690080)

Antigène: NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOSTRIN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NOSTRIN anticorps

Épitope: AA 430-480

Specificité: NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist, this antibody will detect all four isoforms.

Purification: NOSTRIN antibody is affinity chromatography purified via peptide column.

Immunogène: NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN.

The immunogen is located within amino acids 430 - 480 of NOSTRIN.

Isotype: IgG

Information d'application

Indications d'application: NOSTRIN antibody can be used for detection of NOSTRIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NOSTRIN antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: NOSTRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur NOSTRIN

Antigène: NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))

Autre désignation: NOSTRIN

Sujet: NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localisation and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5).

Poids moléculaire: Predicted: 47, 53, 56, 62 kDa

Observed: 68 kDa

ID gène: 115677

NCBI Accession: NP_443178

UniProt: Q8IVI9