PIK3R4 anticorps (AA 1290-1340)

N° du produit ABIN5690100

Cet anticorps Lapin Polyclonal détecte spécifiquement PIK3R4 dans ELISA, WB, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PIK3R4 anticorps (AA 1290-1340) (ABIN5690100)

Antigène: PIK3R4 (Phosphoinositide 3-kinase Regulatory Subunit 4 (PIK3R4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PIK3R4 anticorps

Épitope: AA 1290-1340

Specificité: PIK3R4 antibody is human, mouse and rat reactive.

Purification: PIK3R4 antibody is affinity chromatography purified via peptide column.

Immunogène: PIK3R4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PIK3R4.

The immunogen is located within amino acids 1290 - 1340 of PIK3R4.

Isotype: IgG

Information d'application

Indications d'application: PIK3R4 antibody can be used for detection of PIK3R4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PIK3R4 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PIK3R4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PIK3R4

Antigène: PIK3R4 (Phosphoinositide 3-kinase Regulatory Subunit 4 (PIK3R4))

Autre désignation: PIK3R4

Sujet: PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4, also known as VPS15) is a 150kD adaptor protein that enhances the lipid kinase activity of PIK3 complexes and may be involved in regulating membrane trafficking late in the endocytic pathway and autophagy (1,2). PIK3R4 is ubiquitously expressed and contains 7 WD repeats, 3 HEAT repeats and 1 protein kinase domain (1). PIK3R4 is crucial for VPS34 function and is necessary for autophagosome formation in multicellular animals and reveal an important role of VPS15 in cellular protection against ubiquitin-positive protein aggregates (3-5).

Poids moléculaire: Predicted: 149 kDa

Observed: 140 kDa

ID gène: 30849

NCBI Accession: NP_055417

UniProt: Q99570