RHOT1 anticorps (AA 40-90)

N° du produit ABIN5690226

Cet anticorps Lapin Polyclonal détecte spécifiquement RHOT1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour RHOT1 anticorps (AA 40-90) (ABIN5690226)

Antigène: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RHOT1 anticorps

Épitope: AA 40-90

Specificité: RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist, this antibody will detect all three isoforms.

Purification: RHOT1 antibody is affinity chromatography purified via peptide column.

Immunogène: RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1.

The immunogen is located within amino acids 40 - 90 of RHOT1.

Isotype: IgG

Information d'application

Indications d'application: RHOT1 antibody can be used for detection of RHOT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RHOT1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RHOT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur RHOT1

Antigène: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Autre désignation: RHOT1

Sujet: The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4).

Poids moléculaire: Predicted: 76 kDa

Observed: 78 kDa

ID gène: 55288

NCBI Accession: NP_001028740

UniProt: Q8IXI2