WSB1 anticorps (AA 70-120)

N° du produit ABIN5690325

Cet anticorps Lapin Polyclonal détecte spécifiquement WSB1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour WSB1 anticorps (AA 70-120) (ABIN5690325)

Antigène: WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WSB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-WSB1 anticorps

Épitope: AA 70-120

Specificité: WSB1 antibody is human specific.

Purification: WSB1 antibody is affinity chromatography purified via peptide column.

Immunogène: WSB1 antibody was raised against a 16 amino acid peptide near the amino terminus of human WSB1.

The immunogen is located within amino acids 70 - 120 of WSB1.

Isotype: IgG

Information d'application

Indications d'application: WSB1 antibody can be used for detection of WSB1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: WSB1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: WSB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur WSB1

Antigène: WSB1 (WD Repeat and SOCS Box Containing 1 (WSB1))

Autre désignation: WSB1

Sujet: The WD repeat and SOCS box-containing 1 (WSB1, also known as SWIP1), is a member of the WD-protein subfamily (1). It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus and expressed as multiple alternatively spliced isoforms (1,2). WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2 (3). Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis (4,5).

Poids moléculaire: Predicted: 46 kDa

Observed: 46 kDa

ID gène: 26118

NCBI Accession: NP_056441

UniProt: Q9Y6I7