Cet anticorps Souris Monoclonal détecte spécifiquement Ovarian Cancer Associated Antigen dans IHC (fro). Il présente une réactivité avec des échantillons de Humain.
OVTL16 recognizes a conformational epitope on ovarian carcinoma membrane antigen OA3 which is present in ovarian carcinomas and in cyst fluids obtained from these carcinomas, as well as in oviductal carcinomas and some endometrial carcinomas
Attributs du produit
A central concept in tumor immunology is that malignancies bear tumor associated antigens, which are not or to a much lesser degree found in normal tissues. These antigens can be used as distinctive markers in diagnosis and therapy. As a consequence, monoclonal antibodies to such antigens may represent useful tools for histopathology, immunoscintigraphy and for immunotherapy.
Immunogène
OVTL16 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with cyst fluid, obtained from a patient with a poorly differentiated Human ovarian carcinoma.
Isotype
IgG1
Indications d'application
OVTL16 is suitable for immunohistochemistry on frozen tissues and for staining with avidin-biotinylated Horseradish peroxidase complex (ABC) as detection reagent. Optimal antibody dilution should be determined by titration
Restrictions
For Research Use only
Buffer
Each vial contains 100 μL 1 mg/mL purified monoclonal antibody in PBS containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.