Bestrophin 1 anticorps (N-Term)

N° du produit ABIN5692801

L’anticorps anti-Bestrophin 1 Polyclonal Lapin est utilisé pour la détection de Bestrophin 1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Bestrophin 1 anticorps (N-Term) (ABIN5692801)

Antigène: Bestrophin 1 (BEST1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Bestrophin 1 anticorps

Épitope: N-Term

Fonction: Anti-Bestrophin/BEST1 Antibody

Séquence: RFIYRLALTE EQQLMFEKLT LYCD

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Bestrophin/BEST1 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Bestrophin, which shares 62.5% amino acid (aa) sequence identity with mouse Bestrophin.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: BEST1

Sujet:

Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Gene Full Name: bestrophin 1

Poids moléculaire: 68 kDa

ID gène: 7439

UniProt: O76090