Cullin 4A anticorps (AA 494-759)

N° du produit ABIN5692838

Cet anticorps anti-Cullin 4A est un anticorps Lapin Polyclonal détectant Cullin 4A dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Cullin 4A anticorps (AA 494-759) (ABIN5692838)

Antigène: Cullin 4A (CUL4A)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 4A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cullin 4A anticorps

Épitope: AA 494-759

Fonction: Anti-Cullin 4a/CUL4A Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Cullin 4a/CUL4A Antibody Picoband® (ABIN5692838). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogène: E. coli-derived human Cullin 4a recombinant protein (Position: M494-A759).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: CUL4A Cullin 4A". 2. Liu L, Lee S, Zhang J, Peters SB, Hannah J, Zhang Y, Yin Y, Koff A, Ma L, Zhou P (May 2009). "CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis". Molecular Cell. 34 (4): 451-60. 3. Shiyanov P, Nag A, Raychaudhuri P (Dec 1999). "Cullin 4A associates with the UV-damaged DNA-binding protein DDB". The Journal of Biological Chemistry. 274 (50): 35309-12.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Cullin 4A

Antigène: Cullin 4A (CUL4A)

Autre désignation: CUL4A

Sujet:

Synonyms: Cullin-4A, CUL-4A, CUL4A

Background: Cullin-4A is a protein that in humans is encoded by the CUL4A gene. It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. As a result, CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. Interestingly, a component of a CUL4A complex, Cereblon, was discovered to be a major target of the teratogenic agent thalidomide.

Poids moléculaire: 88 kDa

ID gène: 8451

UniProt: Q13619