Cullin 4A anticorps (AA 494-759)
Aperçu rapide pour Cullin 4A anticorps (AA 494-759) (ABIN5692838)
Antigène
Voir toutes Cullin 4A (CUL4A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 494-759
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Fonction
- Anti-Cullin 4a/CUL4A Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Cullin 4a/CUL4A Antibody (ABIN5692838). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Immunogène
- E. coli-derived human Cullin 4a recombinant protein (Position: M494-A759).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cullin 4A (CUL4A)
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Autre désignation
- CUL4A
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Sujet
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Synonyms: Cullin-4A, CUL-4A, CUL4A
Background: Cullin-4A is a protein that in humans is encoded by the CUL4A gene. It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. As a result, CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. Interestingly, a component of a CUL4A complex, Cereblon, was discovered to be a major target of the teratogenic agent thalidomide.
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Poids moléculaire
- 88 kDa
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ID gène
- 8451
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UniProt
- Q13619
Antigène
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