HMBS anticorps (AA 6-361)

N° du produit ABIN5692868

Détail du produit anti-HMBS anticorps

Antigène: HMBS (Hydroxymethylbilane Synthase (HMBS))

Épitope: AA 6-361

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMBS est non-conjugé

Application: Western Blotting (WB), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for HMBS detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human HMBS recombinant protein (Position: N6-H361).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot,0.1-0.5 μg/mL
Direct ELISA,0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur HMBS

Antigène: HMBS (Hydroxymethylbilane Synthase (HMBS))

Autre désignation: HMBS (HMBS Produits)

Synonymes: anticorps PBG-D, anticorps PBGD, anticorps PORC, anticorps UPS, anticorps URO-S, anticorps hemC, anticorps pbg-d, anticorps pbgd, anticorps ups, anticorps SPAC806.01, anticorps DDBDRAFT_0186148, anticorps DDBDRAFT_0231417, anticorps DDB_0186148, anticorps DDB_0231417, anticorps Hmbs, anticorps NV50236, anticorps T25658, anticorps Ups, anticorps Uros1, anticorps hmbs, anticorps zgc:64128, anticorps hmbsl, anticorps id:ibd5004, anticorps im:7140060, anticorps zgc:110690, anticorps hydroxymethylbilane synthase, anticorps hydroxymethylbilane synthase S homeolog, anticorps hydroxymethylbilane synthase L homeolog, anticorps hydroxymethylbilane synthase (predicted), anticorps Hydroxymethylbilane synthase, anticorps hydroxymethylbilane synthase a, anticorps hydroxymethylbilane synthase, b, anticorps HMBS, anticorps Hmbs, anticorps hmbs, anticorps hmbs.2.S, anticorps hmbs.L, anticorps CNC02250, anticorps hem3, anticorps hemC, anticorps Trad_0335, anticorps Plabr_2100, anticorps Sgly_3113, anticorps SMLT_RS19660, anticorps PMI_RS16580, anticorps hmbsa, anticorps hmbsb

Sujet:

Synonyms: Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase, HMBS, PBGD, UPS

Tissue Specificity: Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells.

Background: Porphobilinogen deaminase (hydroxymethylbilane synthase, or uroporphyrinogen I synthase) is an enzyme that in humans is encoded by the HMBS gene. This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

UniProt: P08397