IL18BP anticorps (AA 29-193)
Aperçu rapide pour IL18BP anticorps (AA 29-193) (ABIN5692876)
Antigène
Voir toutes IL18BP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 29-193
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Fonction
- Anti-IL18 binding protein/Il18bp Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-IL18 binding protein/Il18bp Antibody Picoband® (ABIN5692876). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Immunogène
- E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. "Entrez Gene: IL18BP interleukin 18 binding protein". 2. Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M (Mar 1999). "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response". Immunity. 10 (1): 127-36. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL18BP (Interleukin 18 Binding Protein (IL18BP))
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Autre désignation
- Il18bp
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Sujet
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Synonyms: Interleukin-18-binding protein, IL-18BP, Interferon gamma-inducing factor-binding protein, Il18bp, Igifbp
Tissue Specificity: Ubiquitous.
Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Poids moléculaire
- 43 kDa
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ID gène
- 16068
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UniProt
- Q9Z0M9
Antigène
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