IQGAP2 anticorps (AA 1329-1544)
Aperçu rapide pour IQGAP2 anticorps (AA 1329-1544) (ABIN5692877)
Antigène
Voir toutes IQGAP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1329-1544
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Fonction
- Anti-IQGAP2 Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-IQGAP2 Antibody Picoband® (ABIN5692877). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Immunogène
- E. coli-derived human IQGAP2 recombinant protein (Position: A1329-Q1544).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section),0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: IQGAP2 IQ motif containing GTPase activating protein 2". 2. Brill S, Li S, Lyman CW, Church DM, Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ (Sep 1996)."The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases". Mol. Cell. Biol. 16 (9): 4869-78. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IQGAP2 (IQ Motif Containing GTPase Activating Protein 2 (IQGAP2))
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Autre désignation
- IQGAP2
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Sujet
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Synonyms: Ras GTPase-activating-like protein IQGAP2, IQGAP2
Tissue Specificity: Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.
Background: Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene. This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 181 kDa
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ID gène
- 10788
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UniProt
- Q13576
Antigène
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