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Interleukin 17a anticorps (AA 26-158)

L’anticorps Lapin Polyclonal anti-Interleukin 17a a été validé pour ELISA, WB et IHC. Il convient pour détecter Interleukin 17a dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN5692879

Aperçu rapide pour Interleukin 17a anticorps (AA 26-158) (ABIN5692879)

Antigène

Voir toutes Interleukin 17a (IL17A) Anticorps
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivité

  • 94
  • 59
  • 17
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
Humain, Souris, Rat

Hôte

  • 60
  • 52
  • 29
  • 6
  • 2
  • 2
Lapin

Clonalité

  • 84
  • 66
  • 1
Polyclonal

Conjugué

  • 73
  • 22
  • 14
  • 9
  • 9
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Interleukin 17a est non-conjugé

Application

  • 72
  • 54
  • 48
  • 19
  • 16
  • 11
  • 11
  • 10
  • 10
  • 8
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-158

    Fonction

    Anti-IL17/Il17a Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-IL17/Il17a Antibody Picoband® (ABIN5692879). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogène

    E. coli-derived mouse IL17 recombinant protein (Position: A26-A158).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA (Cap), 1-5 μg/mL
    1. "Entrez Gene: IL17A interleukin 17A". 2. Rouvier E, Luciani MF, Mattéi MG, Denizot F, Golstein P (June 1993). "CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene". Journal of Immunology. 150 (12): 5445-56.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    Autre désignation

    Il17a

    Sujet

    Synonyms: Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, Il17a, Ctla8, Il17

    Tissue Specificity: Restricted to a subset of activated T-cells.

    Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    Poids moléculaire

    27 kDa

    ID gène

    16171

    UniProt

    Q62386
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