Neuromedin U anticorps

N° du produit ABIN5692905

Cet anticorps Lapin Polyclonal détecte spécifiquement Neuromedin U dans WB. Il présente une réactivité envers Rat et Souris.

Aperçu rapide pour Neuromedin U anticorps (ABIN5692905)

Antigène: Neuromedin U (NMU)

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuromedin U est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Neuromedin U anticorps

Fonction: Anti-NMU Antibody Picoband®

Séquence: FRVDEEFQSP FASQSRGYFL FRPRN

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human

Attributs du produit: Anti-NMU Antibody Picoband® (ABIN5692905). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human NMU, which shares 64% and 56% amino acid (aa) sequence identity with mouse and rat NMU, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
1. Austin, C., Lo, G., Nandha, K. A., Meleagros, L., Bloom, S. R. Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract. J. Molec. Endocr. 14: 157-169, 1995. 2. Howard, A. D., Wang, R., Pong, S.-S., Mellin, T. N., Strack, A., Guan, X.-M., Zeng, Z., Williams, D. L., Jr., Feighner, S. D., Nunes, C. N., Murphy, B., Stair, J. N., and 13 others. Identification of receptors for neuromedin U and its role in feeding. Nature 406: 70-74, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Neuromedin U

Antigène: Neuromedin U (NMU)

Autre désignation: NMU

Sujet:

Synonyms: Neuromedin-U, Neuromedin-U-25, NmU-25, NMU

Tissue Specificity: Expressed throughout the enteric nervous system with highest levels being found in the jejunum.

Background: Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

Poids moléculaire: 26 kDa

ID gène: 10874

UniProt: P48645

Pathways: Feeding Behaviour, Photoperiodism