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SYT1 anticorps

L’anticorps Lapin Polyclonal anti-SYT1 a été validé pour WB, IHC, ICC et FACS. Il convient pour détecter SYT1 dans des échantillons de Humain, Rat et Souris.
N° du produit ABIN5692948

Aperçu rapide pour SYT1 anticorps (ABIN5692948)

Antigène

Voir toutes SYT1 Anticorps
SYT1 (Synaptotagmin I (SYT1))

Reactivité

  • 87
  • 76
  • 55
  • 11
  • 7
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 90
  • 12
  • 8
  • 6
  • 2
  • 1
  • 1
Lapin

Clonalité

  • 100
  • 20
Polyclonal

Conjugué

  • 66
  • 8
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SYT1 est non-conjugé

Application

  • 67
  • 41
  • 36
  • 15
  • 13
  • 13
  • 12
  • 12
  • 8
  • 8
  • 5
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Fonction

    Anti-Synaptotagmin 1/SYT1 Antibody Picoband®

    Séquence

    RRPIAQWHTL QVEEEVDAML AVKK

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Synaptotagmin 1/SYT1 Antibody Picoband® (ABIN5692948). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human Synaptotagmin 1, identical to the related mouse and rat sequences.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunocytochemistry, 0.5-1 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Fernandez-Chacon, R., Konigstorfer, A., Gerber, S. H., Garcia, J., Matos, M. F., Stevens, C. F., Brose, N., Rizo, J., Rosenmund, C., Sudhof, T. C. Synaptotagmin I functions as a calcium regulator of release probability. Nature 410: 41-49, 2001. 2. Poskanzer, K. E., Marek, K. W., Sweeney, S. T., Davis, G. W. Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo. Nature 426: 559-563, 2003.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    SYT1 (Synaptotagmin I (SYT1))

    Autre désignation

    SYT1

    Sujet

    Synonyms: Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT

    Tissue Specificity: Expressed in melanocytes (PubMed:23999003).

    Background: Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.

    Poids moléculaire

    65 kDa

    ID gène

    6857

    UniProt

    P21579

    Pathways

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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