Neurexin 1 anticorps (AA 141-294)

N° du produit ABIN5693015

Détail du produit anti-Neurexin 1 anticorps

Antigène: Neurexin 1 (NRXN1)

Épitope: AA 141-294

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurexin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Neurexin 1 detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur Neurexin 1

Antigène: Neurexin 1 (NRXN1)

Autre désignation: NRXN1 (NRXN1 Produits)

Synonymes: anticorps Hs.22998, anticorps PTHSL2, anticorps SCZD17, anticorps CG7050, anticorps CT21808, anticorps Dmel\\CG7050, anticorps Nrx, anticorps Nrx1, anticorps dnrx, anticorps dnrx-1, anticorps nrx, anticorps Nrxn1b, anticorps NRXN1, anticorps Nrx-1, anticorps GB13455, anticorps GB18754, anticorps 1700062G21Rik, anticorps 9330127H16Rik, anticorps A230068P09Rik, anticorps mKIAA0578, anticorps neurexin 1, anticorps Neurexin 1, anticorps neurexin I, anticorps neurexin 1b, anticorps neurexin 1a, anticorps NRXN1, anticorps Nrx-1, anticorps Nrxn1, anticorps nrxn1, anticorps nrxn1b, anticorps nrxn1a

Sujet:

Synonyms: Neurexin-1-beta, Neurexin I-beta, NRXN1

Background: Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development