MPZ anticorps (AA 30-153)

N° du produit ABIN5693047

L’anticorps Lapin Polyclonal anti-MPZ a été validé pour WB et ELISA. Il convient pour détecter MPZ dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MPZ anticorps (AA 30-153) (ABIN5693047)

Antigène: MPZ (Myelin Protein Zero (MPZ))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPZ est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MPZ anticorps

Épitope: AA 30-153

Fonction: Anti-Myelin Protein Zero/MPZ Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Myelin Protein Zero/MPZ Antibody Picoband® (ABIN5693047). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogène: E. coli-derived human Myelin Protein Zero recombinant protein (Position: I30-R153).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Lemke G, Axel R (March 1985). "Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin". Cell. 40 (3): 501-8. 2. Sakamoto Y, Kitamura K, Yoshimura K, Nishijima T, Uyemura K (March 1987). "Complete amino acid sequence of P0 protein in bovine peripheral nerve myelin". J. Biol. Chem. 262 (9): 4208-14.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur MPZ

Antigène: MPZ (Myelin Protein Zero (MPZ))

Autre désignation: MPZ

Sujet:

Synonyms: Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ

Tissue Specificity: Found only in peripheral nervous system Schwann cells.

Background: Myelin protein zero (P0, MPZ) is a glycoprotein which in humans is encoded by the MPZ gene. This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism.

Poids moléculaire: 28 kDa

ID gène: 4359

UniProt: P25189