TPMT anticorps (AA 1-245)

N° du produit ABIN5693135

Détail du produit anti-TPMT anticorps

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Épitope: AA 1-245

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPMT est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for TPMT detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human TPMT recombinant protein (Position: M1-K245).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur TPMT

Antigène: TPMT (Thiopurine S-Methyltransferase (TPMT))

Autre désignation: TPMT (TPMT Produits)

Synonymes: anticorps MGC84277, anticorps AW106912, anticorps NHLRC1, anticorps thiopurine S-methyltransferase L homeolog, anticorps thiopurine S-methyltransferase, tandem duplicate 2, anticorps thiopurine S-methyltransferase TpmT, anticorps thiopurine S-methyltransferase, anticorps Thiopurine S-methyltransferase, anticorps thiopurine methyltransferase, anticorps tpmt.L, anticorps tpmt.2, anticorps tpmT, anticorps MCA0794, anticorps Pnap_4948, anticorps Hhal_1383, anticorps TK90_1044, anticorps Slit_1144, anticorps Tint_0842, anticorps Fbal_3334, anticorps Celly_3188, anticorps Weevi_1737, anticorps Psefu_2696, anticorps Metme_3860, anticorps Tpmt, anticorps TPMT

Sujet:

Synonyms: Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT

Background: Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene. This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

UniProt: P51580