CD1c anticorps (AA 73-287)

N° du produit ABIN5693174

Cet anticorps anti-CD1c est un anticorps Lapin Polyclonal détectant CD1c dans WB. Adapté pour Humain.

Aperçu rapide pour CD1c anticorps (AA 73-287) (ABIN5693174)

Antigène: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD1c est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD1c anticorps

Épitope: AA 73-287

Fonction: Anti-CD1c Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CD1c Antibody Picoband® (ABIN5693174). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogène: E. coli-derived human CD1c recombinant protein (Position: K73-L287).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
1. Granelli-Piperno, A., Shimeliovich, I., Pack, M., Trumpfheller, C., Steinman, R. M. HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood. J. Immun. 176: 991-998, 2006. 2. Moody, D. B., Ulrichs, T., Muhlecker, W., Young, D. C., Gurcha, S. S., Grant, E., Rosat, J.-P., Brenner, M. B., Costello, C. E., Besra, G. S., Porcelli, S. A. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature 404: 884-888, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CD1c

Antigène: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Autre désignation: CD1C

Sujet:

Synonyms: T-cell surface glycoprotein CD1c, CD1c, CD1C

Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

Background: CD1C is a group-1 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Poids moléculaire: 62 kDa

ID gène: 911

UniProt: P29017