CDC45 anticorps (AA 166-431)

N° du produit ABIN5693209

Détail du produit anti-CDC45 anticorps

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Épitope: AA 166-431

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC45 est non-conjugé

Application: Western Blotting (WB), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for CDC45L detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human CDC45L recombinant protein (Position: E166-A431).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur CDC45

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Autre désignation: CDC45 (CDC45 Produits)

Synonymes: anticorps cdc45l, anticorps cdc45l2, anticorps porc-pi-1, anticorps CDC45L, anticorps CDC45L2, anticorps PORC-PI-1, anticorps Cdc45l, anticorps cell division cycle 45, anticorps cell division cycle 45 S homeolog, anticorps cell division cycle 45 L homeolog, anticorps cdc45, anticorps CDC45, anticorps cdc45.S, anticorps Cdc45, anticorps cdc45.L

Sujet:

Synonyms: Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2, UNQ374/PRO710

Tissue Specificity: Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.

Background: CDC45 is a protein that in humans is encoded by the CDC45L gene. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

UniProt: O75419

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA