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IL36A/IL1F6 anticorps (AA 6-151)

IL1F6 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5693268
  • Antigène Voir toutes IL36A/IL1F6 (IL1F6) Anticorps
    IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 6-151
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 40
    • 3
    Lapin
    Clonalité
    • 42
    • 1
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp IL36A/IL1F6 est non-conjugé
    Application
    • 22
    • 18
    • 17
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Marque
    Picoband™
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for IL36 alpha detection. Tested with WB, IHC-P, ELISA(Cap) in Human,Mouse,Rat.
    Immunogène
    E. coli-derived human IL36 alpha recombinant protein (Position: K6-D151).
    Top Product
    Discover our top product IL1F6 Anticorps primaire
  • Indications d'application

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Application Details: Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA(Cap), 1-5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
    Autre désignation
    IL36A (IL1F6 Produits)
    Synonymes
    anticorps Il1f6, anticorps Fil1, anticorps IL-1H1, anticorps IL1RP2, anticorps Il1f9, anticorps Il36a, anticorps FIL1, anticorps FIL1(EPSILON), anticorps FIL1E, anticorps IL-1F6, anticorps IL1(EPSILON), anticorps IL1F6, anticorps interleukin 36, alpha, anticorps interleukin 1 family, member 6 (epsilon), anticorps interleukin 1 family, member 6, anticorps interleukin 36 alpha, anticorps Il36a, anticorps IL1F6, anticorps IL36A, anticorps Il1f6
    Sujet

    Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

    Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

    Background: Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

    Pathways
    Cancer Immune Checkpoints
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