DCTN3 anticorps (Internal Region)
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- Antigène Voir toutes DCTN3 (Dctn3) Anticorps
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
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Épitope
- Internal Region
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Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DCTN3 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Séquence
- C-QVALGNISSK RE
- Specificité
- This antibody is expected to recognize both reported isoforms (NP_009165.1, NP_077324.1).
- Réactivité croisée (Details)
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Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse, Rat. - Purification
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Peptide with sequence from the internal region of the protein sequence according to NP_009165.1 and NP_077324.1. Genename: DCTN3
- Top Product
- Discover our top product Dctn3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
- Autre désignation
- Dynactin Subunit 3 (Dctn3 Produits)
- Synonymes
- anticorps zgc:92471, anticorps wu:fc38g10, anticorps p24, anticorps NV12799, anticorps DCTN-22, anticorps DCTN22, anticorps dynactin 3 (p22), anticorps dynactin subunit 3, anticorps dynactin 3, anticorps dctn3, anticorps LOC658790, anticorps Dctn3, anticorps DCTN3
- Sujet
- This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. Transcript Variant: This variant contains an additional 97 nt within the 3' coding region, as compared to variant 1 resulting in a frame-shift. Isoform 2 encoded by this variant has a different, and 10 aa shorter C-terminus than isoform 1.Synonyms: DCTN22, DCTN3
- Poids moléculaire
- 19.5kDa (NP_077324.1).
- ID gène
- 11258
- NCBI Accession
- NP_009165
- UniProt
- O75935
- Pathways
- M Phase
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