TRIM21 anticorps (C-Term)

N° du produit ABIN569661

Détail du produit anti-TRIM21 anticorps

Antigène: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: CPLNIGSQGS TDY

Specificité: Recognizes 52 Kd Ro Protein (TRIM21).

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide (CPLNIGSQGSTDY) from C-terminus of Human TRIM21

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TRIM21

Antigène: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Autre désignation: SS-A / Ro52 / TRIM21 (TRIM21 Produits)

Synonymes: anticorps RNF81, anticorps RO52, anticorps SSA, anticorps SSA1, anticorps Ro52, anticorps Ssa1, anticorps tripartite motif containing 21, anticorps tripartite motif-containing 21, anticorps TRIM21, anticorps Trim21

Sujet: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is part of the RoSSA ribonucleoprotein which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. The function of the RoSSA particle has not been determined. Two alternatively spliced transcript variants for this gene have been described, however, the full length nature of one variant has not been determined.Synonyms: E3 ubiquitin-protein ligase TRIM21, RING finger protein 81, RNF81, Ro(SS-A), SSA1, Sjoegren syndrome type A antigen, TRIM21, Tripartite motif-containing protein 21

ID gène: 6737

NCBI Accession: NP_003132

UniProt: P19474