PROX1 anticorps (C-Term)

N° du produit ABIN569679

Cet anticorps anti-PROX1 Polyclonal Lapin (ABIN569679) détecte spécifiquement PROX1 dans WB, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Poisson.

Aperçu rapide pour PROX1 anticorps (C-Term) (ABIN569679)

Antigène: PROX1 (Prospero Homeobox 1 (PROX1))

Reactivité: Humain, Souris, Rat, Poisson

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PROX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PROX1 anticorps

Épitope: C-Term

Specificité: This antibody is reactive with Prox-1. It will be a useful tool to study lymphatic vessel density in and around human tumors. It will detect Prox-1 in the nucleus of lymphatic endothelial cells.

Purification: Purified

Immunogène: Peptide corresponding to the Homeobox domain of Prox1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store lyophilized (preferably in a desiccator) at -20 °C and in aliquots at -80 °C. Reconstituted antibody can be stored at 4 °C for a limited period of time, it does not show decline in activity after two weeks at 4 °C.

Détails sur PROX1

Antigène: PROX1 (Prospero Homeobox 1 (PROX1))

Autre désignation: PROX-1

Sujet: The homeobox gene Prox-1 was originally cloned by homology to the Drosophila melanogaster gene prospero. Prox-1 is expressed in a subpopulation of endothelial cells which by budding and sprouting, give rise to the lymphatic system. Prox-1-deficient homozygous mice have unaffected vasculogenesis and angiogenesis, but liver and lymphatics do not develop. Human Prox-1 gene has been mapped to chromosome 1q32.2-q32.3, and its product shows 94 % similarity to the chicken protein. The conserved structure and expression pattern of the Prox-1 gene imply that it may play the same roles in humans as in other vertebrates. The human Prox-1 gene is most actively expressed in the developing lens. Anti-Prox-1 antibodies provide a highly specific marker of lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1

ID gène: 5629

NCBI Accession: NP_002754

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation