Interleukin enhancer-binding factor 3 (ILF3) anticorps

N° du produit ABIN5696831

L’anticorps Lapin Polyclonal anti- a été validé pour WB, IHC, ELISA, IP et IF. Il convient pour détecter dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Interleukin enhancer-binding factor 3 (ILF3) anticorps (ABIN5696831)

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit

Fonction: ILF3 antibody

Immunogène: interleukin enhancer binding factor 3, 90kDa

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab04288( NF90,ILF3 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détail du antigène

Antigène: Interleukin enhancer-binding factor 3 (ILF3)

Autre désignation: ILF3

Sujet:

Synonyms: Interleukin enhancer-binding factor 3|Double-stranded RNA-binding protein 76 (DRBP76)|M-phase phosphoprotein 4 (MPP4)|Nuclear factor associated with dsRNA (NFAR)|Nuclear factor of activated T-cells 90 kDa (NF-AT-90)|Translational control protein 80 (TCP80)|ILF3|DRBF|MPHOSPH4|NF90

Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 90 kDa,110 kDa

ID gène: 3609

UniProt: Q12906

Pathways: M Phase