FKBP8 anticorps

N° du produit ABIN5697691

Cet anticorps Lapin Polyclonal détecte spécifiquement FKBP8 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour FKBP8 anticorps (ABIN5697691)

Antigène: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FKBP8 anticorps

Fonction: FKBP8 antibody

Immunogène: FK506 binding protein 8, 38kDa

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur FKBP8

Antigène: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Autre désignation: FKBP8

Sujet:

Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8)|38 kDa FK506-binding protein (38 kDa FKBP, FKBP-38, hFKBP38)|FK506-binding protein 8 (FKBP-8)|FKBPR38|Rotamase|FKBP8|FKBP38

Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Poids moléculaire: 53 kDa

ID gène: 23770

UniProt: Q14318

Pathways: Autophagy