HAX1 anticorps
Aperçu rapide pour HAX1 anticorps (ABIN5697839)
Antigène
Voir toutes HAX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- HAX1 antibody
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Immunogène
- HCLS1 associated protein X-1
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Isotype
- IgG
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Indications d'application
- WB : 1:200-1:1000 IP : 1:200-1:1000 IHC : 1:20-1:200
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Commentaires
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03765( HAX1 Antibody) at dilution of 1:300
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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Autre désignation
- HAX1
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Sujet
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Synonyms: HCLS1-associated protein X-1|HS1-associating protein X-1 (HAX-1)|HS1-binding protein 1 (HSP1BP-1)|HAX1|HS1BP1
Background: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 32 kDa
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ID gène
- 10456
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UniProt
- O00165
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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