IL-10RA anticorps

N° du produit ABIN5698000

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-10RA dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour IL-10RA anticorps (ABIN5698000)

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-10RA est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-IL-10RA anticorps

Fonction: IL10RA antibody

Immunogène: interleukin 10 receptor, alpha

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IL-10RA

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Autre désignation: IL10RA

Sujet:

Synonyms: Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA)|CDw210a|Interleukin-10 receptor subunit 1 (IL-10R subunit 1, IL-10R1)|IL10RA|IL10R

Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Poids moléculaire: 70-72 kDa,90-95 kDa

ID gène: 3587

UniProt: Q13651

Pathways: Growth Factor Binding