RAB7B anticorps

N° du produit ABIN5698229

L’anticorps anti-RAB7B Polyclonal produit chez le Lapin a été validé pour WB, ELISA et IHC. Il convient pour la détection de RAB7B dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour RAB7B anticorps (ABIN5698229)

Antigène: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB7B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RAB7B anticorps

Fonction: RAB7B antibody

Immunogène: RAB7B, member RAS oncogene family

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RAB7B

Antigène: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Autre désignation: RAB7B

Sujet:

Synonyms: Ras-related protein Rab-7b|RAB7B

Background: Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.

ID gène: 338382

UniProt: Q96AH8