RAB7B anticorps
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- Antigène Voir toutes RAB7B Anticorps
- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RAB7B est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogène
- RAB7B, member RAS oncogene family
- Isotype
- IgG
- Top Product
- Discover our top product RAB7B Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
- Stock
- -20 °C
- Date de péremption
- 12 months
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- Antigène
- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
- Autre désignation
- RAB7B (RAB7B Produits)
- Synonymes
- anticorps RGD1562617, anticorps RAB7B, anticorps RAB7, anticorps Rab7b, anticorps Rab7b, member RAS oncogene family, anticorps rab7B protein, anticorps RAB7B, member RAS oncogene family, anticorps RAB7B, member RAS oncogene family S homeolog, anticorps Rab7b, anticorps rab7B, anticorps RAB7B, anticorps rab7b.S, anticorps rab7b
- Sujet
- Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
- ID gène
- 338382
- UniProt
- Q96AH8
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