ADAR anticorps

N° du produit ABIN5699808

Cet anticorps anti-ADAR est un anticorps Lapin Polyclonal détectant ADAR dans WB, IHC, ELISA, IF et IP. Adapté pour Humain, Souris, Rat et Porc.

Aperçu rapide pour ADAR anticorps (ABIN5699808)

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivité: Humain, Souris, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-ADAR anticorps

Fonction: ADAR antibody

Immunogène:

Immunogen sequence: Peptide

Immunogen: adenosine deaminase, RNA-specific

Isotype: IgG

Information d'application

Indications d'application: WB :1:500-1:5000,IHC:1:20-1:200,IP:1:200-1:2000,IF:1:20-1:200

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00150( ADAR1 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ADAR

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Autre désignation: ADAR

Sujet:

Synonyms: Double-stranded RNA-specific adenosine deaminase (DRADA)|136 kDa double-stranded RNA-binding protein (p136)|Interferon-inducible protein 4 (IFI-4)|K88DSRBP|ADAR|ADAR1|DSRAD|G1P1|IFI4

Background: ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

Poids moléculaire: 136kDa,observed 110kDa

UniProt: P55265

Pathways: Protein targeting to Nucleus