LIMS1 anticorps
Aperçu rapide pour LIMS1 anticorps (ABIN5703373)
Antigène
Voir toutes LIMS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- LIMS1 antibody
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Immunogène
- LIM and senescent cell antigen-like domains 1
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04782(LIMS1 antibody) at dilution of 1:400
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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Autre désignation
- LIMS1
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Sujet
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Synonyms: LIM and senescent cell antigen-like-containing domain protein 1|Particularly interesting new Cys-His protein 1 (PINCH-1)|Renal carcinoma antigen NY-REN-48|LIMS1|PINCH|PINCH1
Background: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 35-37 kDa
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ID gène
- 3987
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UniProt
- P48059
Antigène
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