MAPKBP1 anticorps

N° du produit ABIN5704705

Cet anticorps Lapin Polyclonal détecte spécifiquement MAPKBP1 dans WB, IHC, ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MAPKBP1 anticorps (ABIN5704705)

Antigène: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-MAPKBP1 anticorps

Fonction: MAPKBP1 antibody

Immunogène: mitogen-activated protein kinase binding protein 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05000(MAPKBP1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MAPKBP1

Antigène: MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))

Autre désignation: MAPKBP1

Sujet:

Synonyms: Mitogen-activated protein kinase-binding protein 1|JNK-binding protein 1 (JNKBP-1)|MAPKBP1|JNKBP1|KIAA0596

Background: MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Poids moléculaire: 200-230 kDa

ID gène: 23005

UniProt: O60336