MBNL3 anticorps

N° du produit ABIN5705442

Détail du produit anti-MBNL3 anticorps

Antigène: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogène: muscleblind-like 3 (Drosophila)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05041( MBNL3 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur MBNL3

Antigène: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Autre désignation: MBNL3 (MBNL3 Produits)

Synonymes: anticorps A530038J18Rik, anticorps AI661274, anticorps CHCR, anticorps E430034C16Rik, anticorps MBLX, anticorps MBLX39, anticorps MBXL, anticorps mbxl, anticorps RGD1565834, anticorps muscleblind like splicing regulator 3, anticorps muscleblind like splicing factor 3, anticorps Muscleblind-like protein 3-like, anticorps muscleblind-like splicing regulator 3, anticorps MBNL3, anticorps Mbnl3, anticorps mbnl3

Sujet: Synonyms:CHCR, MBLX39, MBXL Background:Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T(TNNT2) pre-mRNA exon inclusion but induces insulin receptor(IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology(DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Poids moléculaire: 38 kDa

ID gène: 55796

UniProt: Q9NUK0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development