HBG1 anticorps (N-Term)

N° du produit ABIN5706737

N° du produit (Fournisseur): 200-301-gs6

L’anticorps Souris Monoclonal anti-HBG1 a été validé pour ELISA et WB. Il convient pour détecter HBG1 dans des échantillons de Humain.

Aperçu rapide pour HBG1 anticorps (N-Term) (ABIN5706737)

Antigène: HBG1 (Hemoglobin, gamma A (HBG1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HBG1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Clone: 4B3-B5-F3-B7

Détail du produit anti-HBG1 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 200-301-gs6

Fournisseur: Rockland

Fonction: Hemoglobin beta F Antibody

Réactivité croisée (Details): This protein A purified mouse monoclonal antibody reacts specifically with human HbF gamma isoform.

Attributs du produit: Synonyms: mouse anti-HbF antibody, mouse anti-hemoglobin antibody, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1, HBG2, HbF Antibody, Sickle Cell Disease (SCD)

Purification: Anti-HbF is purified from tissue culture supernatant by protein A purification.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Anti-Hemoglobin beta F Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb beta-subunit conjugated to KLH.

Immunogen Type: Conjugated Peptide

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Application Note: Anti-Hemoglobin beta F (MOUSE) antibody has been tested ELISA and Western Blotting. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1:20,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur HBG1

Antigène: HBG1 (Hemoglobin, gamma A (HBG1))

Autre désignation: HBG1

Sujet: Background: HbF antibodies detect the hemoglobin gamma isoform subunit. Functional alternate hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 gamma subunits (alpha-2 gamma-2). Hemoglobin F is elevated in newborns, reaching adult levels by 12 months. HbF levels are increased to as much as 5 % to 10 % in normal pregnancy. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Hemoglobin variants arise from mutations in the globin genes and sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. HbF antibody does not react other forms of Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.

ID gène: 3047

NCBI Accession: NP_000550

UniProt: P69891