Recombinant Thrombomodulin anticorps (AA 69-194)
Aperçu rapide pour Recombinant Thrombomodulin anticorps (AA 69-194) (ABIN5707539)
Antigène
Voir toutes Thrombomodulin (THBD) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 69-194
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Fonction
- Recombinant Thrombomodulin Antibody / CD141 (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogène
- Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this recombinant Thrombomodulin antibody.
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Isotype
- IgG1, kappa
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Indications d'application
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant Thrombomodulin antibody to be titered up or down for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant Thrombomodulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Thrombomodulin (THBD)
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Autre désignation
- Thrombomodulin
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Sujet
- It recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
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UniProt
- P07204
Antigène
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