Nkx2-2 anticorps (AA 1-119)

N° du produit ABIN5707916

Cet anticorps Souris Monoclonal détecte spécifiquement Nkx2-2 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Nkx2-2 anticorps (AA 1-119) (ABIN5707916)

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Nkx2-2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RMNK2-2

Détail du produit anti-Nkx2-2 anticorps

Épitope: AA 1-119

Purification: Purified

Pureté: Protein G affinity chromatography

Immunogène: A human partial recombinant protein corresponding to amino acids 1-119 was used as the immunogen for this NKX2.2 antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titering of the NKX2.2 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Nkx2-2

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Autre désignation: NKX2.2

Sujet: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

ID gène: 4821

Pathways: Dopaminergic Neurogenesis