Tyrosinase-Related Protein 1 anticorps (TRP1)
Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (TRP1) (ABIN5708051)
Antigène
Voir toutes Tyrosinase-Related Protein 1 (TYRP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 257-377, TRP1
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Purification
- Purified
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Pureté
- Protein A affinity chromatography
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Immunogène
- A portion of amino acids 257-377 was used as the immunogen for this recombinant TRP1 antibody.
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Isotype
- IgG kappa
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Indications d'application
- The optimal dilution of the recombinant TRP1 antibody for each application should be determined by the researcher.\. Immunohistochemistry (FFPE) : 1-2 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)
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Restrictions
- For Research Use only
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant TRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Tyrosinase-Related Protein 1 (TYRP1)
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Autre désignation
- Tyrosinase-Related Protein-1
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Sujet
- Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Antigène
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