SLAMF1 anticorps (APC)
Aperçu rapide pour SLAMF1 anticorps (APC) (ABIN5711611)
Antigène
Voir toutes SLAMF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD150 APC
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Réactivité croisée (Details)
- Human
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Attributs du produit
- The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
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Purification
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogène
- Human CD150-transfected 300.19 cells
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Isotype
- IgG1
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Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze,Protect from prolonged exposure to light
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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Autre désignation
- CD150
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Sujet
- Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1
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ID gène
- 6504
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UniProt
- Q13291
Antigène
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