GABBR1 anticorps (AA 947-961)

N° du produit ABIN574068

Détail du produit anti-GABBR1 anticorps

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Épitope: AA 947-961

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Singe, Porc, Hamster, Chien, Cheval, Lapin, Roussette (Chauve-souris)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human GABBR1. This antibody is expected to recognize reported isoforms a, b and c (NP_001461.1, NP_068703.1, NP_068704.2 resp.).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig (100%) Phytophthora (80%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide DRLSCDGSRVHLLYK from the C-terminus of human GABBR1 (NP_001461.1, NP_068703.1, NP_068704.2, NP_068705.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig (100%), Phytophthora (80%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (3.75 - 5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 to 5 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur GABBR1

Antigène: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Autre désignation: GABABR1 / GABBR1 (GABBR1 Produits)

Synonymes: anticorps GABABR1, anticorps GABBR1-3, anticorps GB1, anticorps GPRC3A, anticorps dJ271M21.1.1, anticorps dJ271M21.1.2, anticorps gabbr1, anticorps GABBR1, anticorps GABA(B)R1, anticorps GABAB1, anticorps GABAbR1, anticorps bM573K1.1, anticorps gamma-aminobutyric acid type B receptor subunit 1, anticorps gamma-aminobutyric acid (GABA) B receptor, 1a, anticorps gamma-aminobutyric acid (GABA) B receptor, 1, anticorps GABBR1, anticorps gabbr1a, anticorps gabbr1, anticorps Gabbr1

Sujet: Name/Gene ID: GABBR1
Subfamily: GABA(B)
Family: GPCR

Synonyms: GABBR1, DJ271M21.1.1, DJ271M21.1.2, GABA(B) receptor, Gaba-b-r1a, GABA-BR1, Gaba-br1a receptor, GABAB, subunit 1c, GABAB1, GABA-B receptor 1, Gaba-b1, Gababr1 receptor, GPRC3A, Gabab-receptor subunit 1a, GABABR1, GABBR1-3, GBR1, HGB1a, GABA-B-R1, GB1

ID gène: 2550

NCBI Accession: NP_001461, NP_068703, NP_068704, NP_068705

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process