GAP43 anticorps

N° du produit ABIN576411

Cet anticorps anti-GAP43 est un anticorps Souris Monoclonal détectant GAP43 dans IHC, IHC (p), FACS et IHC (fro). Adapté pour Rat, Souris et Poulet.

Aperçu rapide pour GAP43 anticorps (ABIN576411)

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivité: Rat, Souris, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GAP43 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GAP43 anticorps

Specificité: Recognizes a protein originally termed 2G13P which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kD laminin receptor precursor or Laminin receptor 1. 40S ribosomal protein SA is a 296 amino acid ~37kD membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor. In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture. 40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility. Has been used for the detection of growth cones by immunohistochemistry and identification of 40S ribosomal protein SA by western blotting in chicken and rat samples.

Immunogène: Embryonic chick tectal membranes.

Type of Immunogen: Membrane fraction

Isotype: IgM

Information d'application

Indications d'application: Approved: Flo, IHC, IHC-Fr, IHC-P

Usage: Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Commentaires:

Target Species of Antibody: Chicken

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tissue culture supernatant, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur GAP43

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Autre désignation: GAP43

Sujet: Name/Gene ID: GAP43
Family: Neuromodulin

Synonyms: GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1

ID gène: 2596