ADK anticorps (AA 22-362)

N° du produit ABIN5775897

Cet anticorps Souris Monoclonal détecte spécifiquement ADK dans WB, ELISA, IF, ICC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ADK anticorps (AA 22-362) (ABIN5775897)

Antigène: ADK (Adenosine Kinase (ADK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AT4F8

Détail du produit anti-ADK anticorps

Épitope: AA 22-362

Fonction: Human Adenosine Kinase/ADK antibody

Purification: Purified

Immunogène: Recombinant human ADK (22-362aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur ADK

Antigène: ADK (Adenosine Kinase (ADK))

Autre désignation: Adenosine Kinase/ADK

Sujet: Adenosine kinase (ADK) is the key regulator of adenosine metabolism. Because of the manifold receptor-dependent actions of adenosine, tight regulation of adenosine levels is crucial. The intracellular and extracellular pools of adenosine are in dynamic exchange by equilibrative and concentrative nucleoside transporters, so extracellular concentrations of adenosine are regulated by interplay of theses transporters with intracellular and extracellular enzymes of adenosine metabolism. Thus, the extracellular concentration of adenosine is enhanced by inhibition of equilibrative nucleoside transporters such as S- (4-nitrobenzyl) -6-thioinosine and cannabidiol and, stimulation of extracellular ATP breakdown and inhibition of intracellular adenosine removal.

NCBI Accession: NP_006712

Pathways: Ribonucleoside Biosynthetic Process