CBR1 anticorps (AA 1-277)
Aperçu rapide pour CBR1 anticorps (AA 1-277) (ABIN5775915)
Antigène
Voir toutes CBR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-277
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Fonction
- Human Carbonyl reductase 1/CBR1 antibody
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Purification
- Purified
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Immunogène
- Recombinant human CBR1 (1-277 aa ) purified from E. coli
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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Autre désignation
- Carbonyl reductase 1/CBR1
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Sujet
- Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).
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NCBI Accession
- NP_001748
Antigène
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