CACYBP
Reactivité: Humain, Souris, Rat
WB, IF, ICC, IP, FACS
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Antigène
CACYBP
(Calcyclin Binding Protein (CACYBP))
Autre désignation
CACYBP
Sujet
CACYBP (Calcyclin-binding protein) is primarily a nuclear protein that contains one CS domain and one SGS domain. CACYBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.