HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) anticorps

N° du produit ABIN5775951

Cet anticorps Souris Monoclonal détecte spécifiquement dans WB, ELISA, ICC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) anticorps (ABIN5775951)

Antigène: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT5D6

Détail du produit

Épitope: AA 1-242

Fonction: Human TIP30/HTATIP2 antibody

Purification: Purified

Immunogène: Recombinant human HTATIP2 (1-242aa) purified from E. coli

Isotype: IgG2a kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Autre désignation: TIP30/HTATIP2

Sujet: HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.