ING2 anticorps (AA 1-280)

N° du produit ABIN5776013

Cet anticorps anti-ING2 est un anticorps Souris Monoclonal détectant ING2 dans WB, ELISA, IF et ICC. Adapté pour Humain.

Aperçu rapide pour ING2 anticorps (AA 1-280) (ABIN5776013)

Antigène: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ING2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT39E5

Détail du produit anti-ING2 anticorps

Épitope: AA 1-280

Fonction: Human ING2 antibody

Purification: Purified

Immunogène: Recombinant human ING2 (1-280aa) purified from E. coli

Isotype: IgG1b kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur ING2

Antigène: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Autre désignation: ING2

Sujet: ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.

NCBI Accession: NP_001555

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling