SOD1 anticorps (AA 1-154)
Aperçu rapide pour SOD1 anticorps (AA 1-154) (ABIN5776029)
Antigène
Voir toutes SOD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-154
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Fonction
- Human SOD1/Cu-Zn SOD antibody
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Purification
- Purified
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Immunogène
- Recombinant human SOD1 (1-154aa) purified from E. coli
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Isotype
- IgG1 kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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Autre désignation
- SOD1/Cu-Zn SOD
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Sujet
- Cu/Zn superoxide dismutase (SOD1), is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. SOD1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. Also over 100 distinct SOD1 inherited mutations have been identified in the familial form of amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear.
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NCBI Accession
- NP_000445
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Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
Antigène
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