FUBP1 anticorps (AA 279-448)

N° du produit ABIN5776101

Cet anticorps Souris Monoclonal détecte spécifiquement FUBP1 dans WB, IF, ELISA et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour FUBP1 anticorps (AA 279-448) (ABIN5776101)

Antigène: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FUBP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Clone: AT14F5

Détail du produit anti-FUBP1 anticorps

Épitope: AA 279-448

Fonction: Human FUBP1 antibody

Immunogène: Recombinant human FUBP1 (279-448aa) purified from E.coli

Isotype: IgG2b kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur FUBP1

Antigène: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Autre désignation: FUBP1

Sujet: FUBP1 is a transcriptional regulator and fulfills an important function in the precise control of c-myc transcription. The c-Myc protein is a transcription factor which regulates the transcription of many different target genes that play a role in proliferation, cell cycle progression, differentiation, apoptosis and cell metabolism. Consequently, FUBP1 is also involved in the regulation of proliferation and differentiation, as confirmed by different experimental approaches. Knockdown of FUBP1 or expression of a dominant-negative FUBP1 (DNA-binding domain lacking effector activity) led to proliferation arrest in U2OS and Saos-2 osteosarcoma cells due to reduced c-myc expression.

NCBI Accession: NP_003893