TPMT anticorps (AA 1-245)
Aperçu rapide pour TPMT anticorps (AA 1-245) (ABIN5776128)
Antigène
Voir toutes TPMT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 1-245
-
Immunogène
- Recombinant human TPMT (1-245aa) purified from E. coli
-
Isotype
- IgG1 kappa
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Stock
- 4 °C,-20 °C,-80 °C
-
Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
-
- TPMT (Thiopurine S-Methyltransferase (TPMT))
-
Autre désignation
- TPMT
-
Sujet
- TPMT (Thiopurine S-methyltransferase) is a very important enzyme for the metabolizm of thiopurine compounds. TPMT pharmacogenetics has been studied extensively because of its clinical significance. Many patients got benefited from the knowledge of TPMT genotype-phenotype correlation. Also, TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.
-
NCBI Accession
- NP_000358
Antigène
-