GCLM anticorps (AA 1-274)

N° du produit ABIN5776191

Cet anticorps Souris Monoclonal détecte spécifiquement GCLM dans WB, ELISA, IF et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour GCLM anticorps (AA 1-274) (ABIN5776191)

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GCLM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT2D12

Détail du produit anti-GCLM anticorps

Épitope: AA 1-274

Immunogène: Recombinant human GCLM (1-274aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur GCLM

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Autre désignation: GCLM

Sujet: GCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer.

NCBI Accession: NP_002052